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Published Papers2019-07-09T11:42:28+00:00

PUBLICATIONS

PUBLISHED PAPERS

L’Occitane – Colonization of a 3D Skin Model

But most of these models are sterile. In recent years, skin microbiota has emerged as a key player in skin health, preventing pathogens proliferation, educating the immune system and maintaining barrier integrity. The first skin models colonized with bacteria have focused on unique bacterial species. But the study of skin diseases (such as atopic dermatitis) revealed that microbiota’s diversity is key to skin health. We thus developed a model that reproduces the complexity of the skin’s ecosystem with an uncultured skin microbiota and compared it to the use of a unique commensal bacteria.

International Journal of Cosmetic Science – 2018 Examination of the Skin Barrier Repair Wound Healing Process

Damage to the structural integrity of the skin through trauma or injury initiates the skin barrier repair/wound healing process, which is highly complex and carefully regulated with ordered responses. There are four main stages involved in the normal skin barrier repair/wound healing process: haemostasis, inflammation, proliferation and remodelling, all of which occur in an over-lapping chronological sequence.

Protoemics Journal – 2018 Mass Spectrometry Imaging of 3D Tissue Models

A 3D cell culture is an artificially created environment in which cells are permitted to grow/interact with their surroundings in all three dimensions. Derived from 3D cell culture, organoids are generally small-scale constructs of cells that are fabricated in the laboratory to serve as 3D representations of in vivo tissues and organs.

Technology Review – Studying the Human Skin Microbiome Using 3D In Vitro Skin Models

Three-dimensional(3D)human skin models are an accepted part of the testing and regulatory landscape in skin related industries and their development, commercialization, and uses have been well documented. At present, there are several established commercial model systems and a multitude of academic lab-specific 3D in vitro reconstructed human skin models, all with different characteristics, strengths, and weaknesses.

Evocutis – 3D Living Skin Models For Product Development

Testing personal care products using clinical trials is the gold standard for proving efficacy, but is often seen as too expensive to be considered cost-effective. However, formal proof that a product works is highly motivating to consumers, as demonstrated by the runaway success of Boots Protect & Perfect anti-ageing serum in 2009.

University of Leeds – Microbial Colonization of an In Vitro Model of a Tissue-Engineered Human Skin Equivalent

Damage to the structural integrity of the skin through trauma or injury initiates the skin barrier repair/wound healing process, which is highly complex and carefully regulated with ordered responses. There are four main stages involved in the normal skin barrier repair/wound healing process: haemostasis, inflammation, proliferation and remodelling, all of which occur in an over-lapping chronological sequence.